Molecular Plant: 2026 Jun 19:S1674-2052(26)00197.
Abstract
The ancestral angiosperm whole-genome duplication (ε-WGD) is a pivotal event that has long been debated. A recent study refuted the ε-WGD based on the retention patterns of dosage-sensitive gene duplicates. However, this study provides both structural (orthologous synteny) and phylogenetic (subgenome-aware) evidence that strongly confirms the genuine occurrence of the ε-WGD event.