A two-session symposium on Advances in phylogenomics and systematics of the Brassicaceae was organized by Martin Lysak and Marcus Koch and sponsored by Annals of Botany. A total of 12 speakers discussed unprecedented advances in systematics, phylogenomics and evolutionary research in the Brassicaceae and shared their most interesting observations and findings with the audience. The opening lecture of the symposium was given by Dr. Ihsan Al-Shehbaz (Missouri Botanic Garden), the world’s leading authority on the taxonomy of the Brassicaceae family. Ihsan gave an amazing talk on the astonishing advances in the systematics and phylogenetics of the Brassicaceae over the last quarter century. Some of the papers presented will appear in the special issue of Annals of Botany, Advances in Crucifer Research in the -Omics Era.